What Is Ketorolac Tromethamine?

Jacquelyn Gilchrist
Jacquelyn Gilchrist

Ketorolac tromethamine is a generic medication marketed under the brand name Toradol® however, this brand may no longer be available in the United States. It is a type of nonsteroidal anti-inflammatory medication (NSAID) that a doctor may prescribe to relieve moderate to severe pain, particularly following a surgical procedure. Ketorolac tromethamine may only be used for short-term pain relief, or no longer than five days. The prescribing physician will likely administer the first dosage as an injection into the muscular tissue and patients may take an oral form of the drug for the next four days.

This drug should never be used before any surgery. It is also contraindicated for use before or after a heart bypass surgery. Ketorolac tromethamine is typically taken every four to six hours, or on an as needed basis. It is essential not to take more of this medicine than prescribed. Those who overdose must get emergency medical care. Symptoms of a possible overdose can include bloody vomit or vomit with the appearance of coffee grounds, as well as loss of consciousness, shallow breathing, and bloody or tarry stools.

Patients should be aware of the possible complications that may develop from using ketorolac tromethamine, which can include ulcers or stomach bleeding. These may sometimes be life-threatening. Ketorolac tromethamine and other NSAIDs may increase the risk of a life-threatening stroke or heart attack, particularly in patients who have high cholesterol or those who smoke. It can also cause kidney failure, which requires emergency medical help. Possible symptoms of kidney failure can include decreased urination, dizziness upon standing, and pain that occurs on one side of the back.

Other side effects can occur with the use of ketorolac tromethamine, which should be reported to the doctor if they become severe. These can include drowsiness, mouth sores, and sweating. Diarrhea, constipation, and flatulence have also been reported. Other patients have experienced headaches and mild dizziness.

More serious side effects require immediate medical care. These can include blistering skin, fever, and jaundice. Pain in the upper right-hand portion of the stomach, rapid heartbeat, and cloudy or bloody urine have also been reported. Patients may notice unusual bleeding or bruising, fatigue, and flu-like symptoms.

Before using ketorolac tromethamine, women must inform their doctors if they are pregnant or breastfeeding. Other medical conditions should be reported, including stomach or intestinal problems, blood disorders, or a history of allergic reactions. Certain other medicines may interact with this drug, including blood thinners, corticosteroids, and some antidepressants.

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