What Is Eszopiclone?

Eszopiclone is prescribed to alleviate insomnia, or difficulty sleeping. It may help patients both fall asleep and be able to sleep through the night. This medication is a central nervous system (CNS) depressant, or a hypnotic. Eszopiclone works by inhibiting the activity of the nervous system.

This drug is available as a tablet taken by mouth. Patients who have trouble sleeping should take one tablet at bedtime. Typically, eszopiclone works quickly to induce sleepiness. This drug should only be taken if patients have a full eight hours to remain in bed, because sleepiness can persist even after waking within this time period.

Eszopiclone is intended as a short-term sleep aid only. Patients should not typically use this drug longer than seven to 10 days, or for no longer than two weeks with a doctor's approval. Those who experience daytime drowsiness may ask for a decreased dosage. A doctor may possibly increase the dosage for patients who still have trouble sleeping. Eszopiclone is not intended for use directly after consuming a high-fat meal, because this may interfere with its efficacy.

Patients who discontinue treatment with this insomnia drug may experience rebound insomnia, which is increased difficulty sleeping. They should refrain from taking another sleep aid, as this condition usually only lasts one to two days. In addition, when discontinuing the drug, patients should decrease the dosage gradually. Withdrawal effects from abrupt discontinuation may include anxiety, vomiting, and shakiness. Rarely, seizures have also been known to occur.

Some side effects may occur with the use of eszopiclone, which should be discussed with the physician if they are persistent or become troublesome. Patients may experience nausea, vomiting, and an unpleasant taste, along with a headache. Unusual dreams, painful menstruation, or male breast enlargement may also occur. Some people have noticed daytime drowsiness, loss of coordination, and heartburn, along with dizziness.

Rarely, sleepwalking or “sleep-driving” have occurred with the use of eszopiclone. This is often accompanied with a loss of memory for the event. Patients have consumed food, driven their cars, and engaged in sexual intercourse while not completely awake. A person who believes this may have happened to him should contact his doctor immediately.

Other rare, but serious, side effects may occur that require a doctor's urgent care. These may include hallucinations, suicidal thoughts, and unusual mood changes, such as depression. Some patients have also experienced symptoms of a possible infection, such as a sore throat, chills, and a fever.

Before taking eszopiclone, patients should disclose their other medical conditions, medications, and supplements. Women who are pregnant or breastfeeding should avoid it. The drug is also contraindicated for use by those who have lung disease, mood disorders, or a history of drug or alcohol abuse. It may interact with other medications, including certain antibiotics, antifungals, and any other drugs that can cause drowsiness.