We are independent & ad-supported. We may earn a commission for purchases made through our links.

Advertiser Disclosure

Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.

How We Make Money

We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently from our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

What is Vigabatrin?

By J.M. Densing
Updated May 17, 2024
Our promise to you
WiseGeek is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At WiseGeek, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

Vigabatrin is an anticonvulsant medication used to control or reduce the frequency of seizures in patients with epilepsy. It is also known by the brand name Sabril, and it works by increasing the levels of a calming chemical called gamma-aminobutyric acid in the brain. The effects of vigabatrin on an unborn child is unknown so it is recommended that pregnant women avoid taking it, and patients should be sure to discuss their complete medical history with their doctor to avoid possible complications. This medication is known to cause permanent vision changes so patients need to have regularly scheduled eye exams while using it. Other side effects include dizziness, drowsiness, altered mood, and digestive discomfort.

Also known as an anti-epileptic, the anticonvulsant medication vigabatrin is usually used along with other medicines to control the incidence and frequency of seizures in epilepsy patients. This drug can be used alone mainly for the treatment of infantile spasms in children under two years old. Vigabatrin is usually implicated after other medications have been found ineffective for control of seizure activity. It works by reducing the breakdown of a natural calming chemical known as gamma-aminobutyric acid (GABA) so that the levels remain higher; low GABA levels have been linked to increased incidence of seizures. It comes in a tablet form or as a powder that must be mixed with water to make an oral solution for infant use.

Women who are pregnant or breastfeeding are advised not to take vigabatrin because the effects on the baby haven't been determined due to a lack of adequate studies on the subject. Patients should be sure to discuss their complete medical history with their doctor to avoid potential complications or drug interactions, especially if vision problems, anemia, mental illness, or kidney disease are present. Vigabatrin is known to cause permanent vision changes which can occur at any time during treatment; in the U.S., it's only prescribed through a restricted program that requires careful vision monitoring. For this reason, patients need to have regularly scheduled eye exams, at least every three months, and be alert for any signs of a problem like blurred or double vision.

Common side effects of vigabatrin include dizziness, drowsiness, confusion, shakiness, joint pain, tingling or prickly sensations, altered mood such as anxiety or depression, and digestive issues. These side effects often go away during treatment. A few rare side effects include headache, difficulty sleeping or concentrating, aggression, nausea, vomiting, weight gain, and disordered thinking. Potentially dangerous side effects that require medical attention as soon as possible include vision changes, eye pain, memory problems, increased seizures, and altered mental status.

WiseGeek is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.

Discussion Comments

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.