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What Is Prednisolone Sodium Phosphate?

By Jacquelyn Gilchrist
Updated: May 17, 2024

Prednisolone sodium phosphate is a medication called a corticosteroid hormone, or a glucocorticoid. This drug works by affecting the immune system's response to inflammatory triggers in order to reduce symptoms like allergic reactions and swelling. A doctor may prescribe it to treat a variety of conditions, including allergies, asthma, and arthritis. Prednisolone sodium phosphate may also help patients with some skin and eye conditions, as well as blood, immune system, or hormone disorders.

Patients must ensure that their hands are dry before handling the medication, as it dissolves in water. It may be swallowed whole with a glass of water, or a patient may place the tablet on top of his tongue until it has fully dissolved. Adults may be prescribed one dose daily, which should be taken in the morning. The doctor may recommend that the patient take the dose with food.

Some side effects may occur while using prednisolone sodium phosphate, which should be reported to the prescribing physician if they become severe. Patients may experience stomach upset, increased appetite, and weight gain. Dizziness, headaches, and insomnia may also occur. Menstrual changes have been reported, such as irregular or delayed periods.

More serious side effects may also occur, which require immediate medical help. These can include vomit with the appearance of coffee grounds, black stools, and persistent weight gain. A rapid or irregular heart beat, slow wound healing, and bone, muscle, or joint pain have also been reported. Some patients have rarely experienced vision changes, thinning hair, and unusual skin growths. Other potentially serious side effects may include swelling of the feet or ankles, mood changes, and a puffy face.

Certain precautions should be taken while using prednisolone sodium phosphate. The doctor may order some laboratory tests to check for side effects, such as a adrenal function test. Those with diabetes should be aware that this drug can affect blood sugar levels. Patients must avoid receiving a live vaccination. This drug can suppress the immune system and render a person more susceptible to contracting infections.

Before using prednisolone sodium phosphate, patients must disclose their other medical conditions, medications, and supplements. Women who are pregnant should avoid this drug, and those who are breastfeeding should discuss potential risks with their doctors. This medication may be contraindicated for use by those who have low blood minerals, high blood pressure, or osteoporosis. Other drugs may interact with prednisolone sodium phosphate, including birth control pills, nonsteroidal anti-inflammatory drugs (NSAIDs), and aspirin.

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