We are independent & ad-supported. We may earn a commission for purchases made through our links.

Advertiser Disclosure

Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.

How We Make Money

We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently from our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

What is Marcaine®?

Tricia Christensen
Updated May 17, 2024
Our promise to you
WiseGeek is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At WiseGeek, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

Marcaine® is one name for a drug manufactured by the company AstraZenca® that contains the active medicine bupivacaine. Although its use is limited to a few, specific medical conditions, it is a popular medication. Principally, Marcaine® is administered in spinal injections as part of local anesthesia. It is highly effective at inducing numbness through a variety of spinal or epidural blocks prior to surgeries.

Since Marcaine® is delivered only by injection or through a catheter into the spinal space, people won’t use this medicine at home and won’t need to worry about dosing. The appropriate dosage and decision whether Marcaine® is the right drug is made by anesthesiologists in most cases. If a surgery is planned where an epidural or spinal block is needed, anesthesiologists would likely call or meet with patients in advance of the surgery, and take a full medical history to can rule out using certain drugs. Bupivacaine might not be considered for those with spinal irregularities, syphilis, arthritis, or diseases or treatment that affect blood-clotting time.

Marcaine® is often contraindicated for use when women are pregnant because it can have toxic effects on the fetus. Despite this, bupivacaine can be used for epidurals during labor or delivery. There is some caution about using the drug at its highest dose, so dose strengths are typically lower. This means additional medicines like opioids might be given in combination with the local anesthetic drug.

Since people ordinarily receive bupivacaine in hospital or clinic settings, they are usually under careful watch by medical personnel. This is important for several reasons. If there are adverse reactions to the drug like seizure or a weakened heart rate, this matter can be medically addressed. Additionally, people who have local anesthetic administered into the spinal cord usually have extremely restricted movement capacity from the waist down and will not be able to walk until the medication wears off.

A few people also encounter unpleasant, though usually medically insignificant, symptoms when they receive Marcaine®. It’s not unusual for the drug to cause feelings of nausea or vomiting. The back or the head can hurt too, and some people feel dizzy, or disoriented due to lack of feeling in the body. Some people can be allergic to bupivacaine, and symptoms to point out to medical staff at hand are rash, itchiness, swelling of mouth, lips or tongue, and difficult breathing or wheezing.

WiseGeek is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Tricia Christensen
By Tricia Christensen , Writer
With a Literature degree from Sonoma State University and years of experience as a WiseGeek contributor, Tricia Christensen is based in Northern California and brings a wealth of knowledge and passion to her writing. Her wide-ranging interests include reading, writing, medicine, art, film, history, politics, ethics, and religion, all of which she incorporates into her informative articles. Tricia is currently working on her first novel.

Discussion Comments

Tricia Christensen

Tricia Christensen


With a Literature degree from Sonoma State University and years of experience as a WiseGeek contributor, Tricia...
Learn more
WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.