We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

What is Hepatocellular Adenoma?

Niki Acker
Updated May 17, 2024
Our promise to you
WiseGeek is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At WiseGeek, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject-matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

Hepatocellular adenoma, also called hepatic adenoma, liver cell adenoma, or hepadenoma, is a benign, or noncancerous, tumor in the liver associated with the use of hormonal contraception with a high estrogen content. Hepatocellular adenoma is extremely rare, affecting less than two in every million people per year, and 90% of cases occur in women aged 20 to 40 who take oral contraceptives. If a hepatocellular adenoma is allowed to grow, it can rupture, causing massive bleeding in the liver. For this reason, and because they may have malignant or cancerous portions, all hepatocellular adenomas should be surgically removed.

Women over 30 who have taken oral contraceptives for over five years have the highest risk of developing a hepatocellular adenoma. People with glycogen storage diseases, both men and women, are also at risk, and men are twice as likely to develop the condition than women within this group. Patients may have only one tumor or many.

Hepatocellular adenoma can cause abdominal pain, as well as the more serious complications discussed above. There may also be a palpable mass in the abdomen, and in the case of hemorrhage, signs of shock including decreased and irregular heartbeat. In a pregnant woman, the condition can result in the death of the fetus or the mother.

Hepatocellular adenoma is usually diagnosed through magnetic resonance imaging (MRI) or a computed tomography (CT) scan. Surgical removal of the lesion is the best way to confirm diagnosis, and can prevent serious complications. A woman diagnosed with hepatocellular adenoma should immediately stop taking birth control, though she should also avoid pregnancy until the liver has been cleared of tumors. The cessation of birth control medication may cause the tumor to regress on its own, but the danger of malignancy still remains.

Surgical removal of hepatic adenoma may be done laparoscopically, through a small incision, if the tumor is small and on the surface of the liver. Most cases of hepatocellular adenoma can be addressed by removing only part of the liver. Liver transplant may be necessary in patients with widespread multiple tumors, or with a glycogen storage disease.

WiseGeek is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Niki Acker
By Niki Acker
"In addition to her role as a WiseGeek editor, Niki Foster is passionate about educating herself on a wide range of interesting and unusual topics to gather ideas for her own articles. A graduate of UCLA with a double major in Linguistics and Anthropology, Niki's diverse academic background and curiosity make her well-suited to create engaging content for WiseGeekreaders. "
Discussion Comments
Niki Acker
Niki Acker
"In addition to her role as a WiseGeek editor, Niki Foster is passionate about educating herself on a wide range of...
Learn more
WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.