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What is Fosamprenavir?

By Jacquelyn Gilchrist
Updated May 17, 2024
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Fosamprenavir is a medication prescribed for patients with human immunodeficiency virus (HIV). While this protease inhibitor drug can help delay the growth of the virus, it cannot cure this condition. Since the patient's immune system will benefit from this drug, it may also help delay the development of other complications related to HIV. These can include tuberculosis, other infections, and neurological complications. Candidates for this treatment may be prescribed other drugs in addition to fosamprenavir.

It is recommended that adults take the tablet on an empty stomach, usually once or twice daily. Those who experience an upset stomach may take the medicine with a meal, however they should only take it with a low-fat meal, as fat can interfere with the drug's absorption. Patients should take each dose at the same time each day. Children who use fosamprenavir are typically prescribed the liquid form of the drug, which should be shaken and then measured with a medicine cup.

Other special precautions must also be followed while using this HIV treatment. Patients should not consume grapefruit or products that contain grapefruit, as this can increase the possibility of side effects. Those who take antacids should discuss this with their physicians, as they may be unable to use antacids close to their next dosage time. Patients who are diabetic should be aware that fosamprenavir may elevate the blood sugar. It may also lessen the efficacy of hormonal birth control, so patients should use a barrier method of birth control.

Fosamprenavir may cause some side effects, including nausea, vomiting, diarrhea, extreme fatigue and headaches, which should be reported to the doctor if they become more severe. Side effects that are potentially more serious will require immediate medical help. Fosamprenavir may cause bloody urine, painful urination, and frequent urination. Extreme thirst or hunger, blurred vision, and decreased consciousness, as well as breath that smells “fruity” may indicate dangerously high blood sugar levels. In addition, other side effects can include problems breathing or swallowing, as well as flu-like symptoms, such as a fever, cough, and chills. Possible signs of an allergic reaction to fosamprenavir may include facial swelling, hives, and a skin rash.

Before taking fosamprenavir, patients should discuss their other medical conditions with the prescribing physician. They may be unable to take this medicine if they also have liver problems, high cholesterol, or diabetes. Those who smoke, have high blood pressure, or a blood disorder may also be unable to use it. This medication should not be used by women who are pregnant. As of 2011, it is unknown whether the drug passes into breast milk.

The prescribing physician should also be aware of other medications and supplements that the patient takes. He may be unable to prescribe this medicine to those who also take St. John's wort, some benzodiazepines, and heart medications. It may also interact with some multivitamins, garlic, and ginseng, as well as St. John's wort, coenzyme Q10, and some herbal teas. Some of these medications may increase the risk of serious side effects.

WiseGeek is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
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