We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

What Is Erythema Annulare Centrifugum?

By H. Colledge
Updated May 17, 2024
Our promise to you
WiseGeek is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At WiseGeek, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject-matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

Erythema annulare centrifugum, or erythema perstans, is a rare condition in which red rings develop on the skin. The cause is often unknown but the disorder is sometimes associated with certain drugs, infections, cancers, and other medical conditions. There may be no symptoms aside from the discolorations, but they are sometimes accompanied by itching, as well as the symptoms of any underlying diseases. The condition usually gets better either by itself or when the underlying disorder is cured. This condition is important because it can indicate the presence of an associated serious disease, such as cancer, that might otherwise be hidden.

Both men and women are equally affected by erythema annulare centrifugum, and the disorder can develop at any age. Skin lesions may occur on any part of the body except the palms of the hands and the soles of the feet, but most often they develop on the legs. Typically, the condition begins with raised red bumps that spread out in a circle while the center clears, forming a red or pink ring. The edge of the circle is thickened and firm, and there may be skin scales on the inner side.

There are a number of different varieties of the condition, and they are sometimes divided into two main types: superficial gyrate erythema and deep gyrate erythema. The superficial type is more frequently seen, and it tends to be itchy and scaly, where the deep type does not itch or form skin scales. Blisters full of fluid may be associated with either form of the condition.

Medicines that have a known association with erythema annulare centrifugum include some antimalarial drugs, aspirin, and penicillin. A bacterial, viral, parasitic, or fungal infection may also cause the disorder, as may an insect bite. Foods such as tomatoes and blue cheese can cause these rings as part of an allergic response. Cancers, particularly lymphomas, are known to cause the condition, and other associated diseases include hyperthyroidism, sarcoidosis and osteoarthritis. Sometimes, the rings develop during pregnancy.

Erythema annulare centrifugum may resolve on its own, and the average length of time before this happens is around 11 months. In some cases, the disorder has been known to disappear in a matter of weeks or to recur over a period of decades. Steroid preparations applied to the skin may help get rid of existing skin lesions but will not prevent new ones from developing. Injected steroids can treat the disorder temporarily, but it soon recurs once the drugs are stopped.

WiseGeek is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Discussion Comments
WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.