We are independent & ad-supported. We may earn a commission for purchases made through our links.

Advertiser Disclosure

Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.

How We Make Money

We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently from our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

What is Anagrelide?

By Dulce Corazon
Updated May 17, 2024
Our promise to you
WiseGeek is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At WiseGeek, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

Anagrelide, with brand name Agrilyn&reg and Xagrid&reg, is a drug often prescribed in patients with essential thrombocythemia (ET), a type of myeloproliferative disorder. Myeloproliferative disorders are conditions characterized by overproduction of blood cells, such as white blood cells, platelets, or red blood cells. In cases of ET, the platelets are usually being produced excessively. The action of anagrelide is mostly directed on the maturation process of the megakaryocyte, the cell where platelets come from. This drug is available in the form 0.5-milligram (mg) capsules.

Platelets, which are small and irregularly-shaped elements present in the blood, are generally important in controlling bleeding during an injury. When there are too many of them in the circulation, such as in individuals with ET, clots can form in some parts of the body, such as the brain and feet. In some instances, this condition can also result in bleeding problems. Signs of bleeding to watch out for include skin bruises, gum bleeding, and presence of blood in the urine and stools.

Patients should strictly follow their doctor's instructions regarding dosage, and when and how long to take anagrelide in order to prevent complications. During the first week of treatment, patients may need to have their platelets counted every couple of days in order for physicians to determine the right amount of medication for each patient. Overdose with this drug can generally lead to lower-than-normal platelet count. When this happens, patients may experience bleeding in the skin and other parts of the body. Other symptoms of overdose include vomiting and increased heart rate.

The side effects of anagrelide include weakness, dizziness, headache, vomiting, and diarrhea. When these symptoms persistently occur, it is often important to inform the doctor. Patients who develop rashes, swallowing difficulty, and swelling of the face often need immediate medical attention as they can be suffering from allergic reactions to the drug. Anagrelide may also have harmful effects on the heart, and can lead to hypertension, chest pain, and other heart problems. This is why patients typically are closely monitored during treatment to evaluate their response to the drug and its effects on them.

Women taking anagrelide are often advised not to get pregnant because this drug is considered harmful to the baby in the womb. Breastfeeding is also not recommended. The effectiveness of anagrelide may also be affected by other drugs, so patients should inform their doctors if they are taking over-the-counter drugs, vitamins, or some food supplements.

WiseGeek is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.

Discussion Comments

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.