What Are the Symptoms of Angelman Syndrome?

Symptoms of Angelman syndrome are not usually present at birth but typically appear before the affected child reaches one year of age. The most common symptoms include developmental delays, physical differences, or abnormal behaviors. Some children with this condition may develop seizures or have problems with motor skills or speech. Those with Angelman syndrome usually have a normal life expectancy, and treatment is aimed at helping the child learn skills that will promote as much independence as possible. Any specific or individualized questions concerning the potential symptoms of Angelman syndrome should be discussed with a doctor or other medical professional.

The first noticeable symptoms of Angelman syndrome typically appear between six months and one year of age. The child with this condition may not crawl or make babbling sounds as expected. Other typical milestones, such as walking and learning to talk, may be significantly delayed. Some degree of mental retardation is common with this syndrome as well, although the full extent of the disability is not able to be diagnosed until the child is older.

Between the ages of two and three, additional symptoms of Angelman syndrome may become apparent. Seizures may begin to occur, and stiff movements or jerky motions may be noticed. The lower jaw may protrude abnormally, or tongue thrusting may begin. The child may often walk around with the arms held in an upward position or flail the arms wildly. The child affected by this disorder frequently seems extraordinarily happy and may laugh and smile almost constantly.

Hyperactivity and extreme excitability are common symptoms of Angelman syndrome. Speech problems are often severe, and the child may only be able to say a few words. Some children with this disorder may never be able to speak at all. Drooling and trouble with the sucking motion are often accompanied by tongue thrusting, making it difficult for the child to eat. The skin or hair may begin to lose pigmentation, and there may be wide gaps between some of the teeth.

Sleep problems are frequently present in those with Angelman syndrome, with patients often functioning on almost no sleep at all. Communication is a major problem, primarily due to the inability to speak that afflicts those with this condition. Communication therapy may be useful in helping the family understand one another. Physical and occupational therapy may also be suggested so that the child can learn to function as independently as possible.