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What are the Side Effects of Prednisolone?

By Lauren Romano
Updated May 17, 2024
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One of the most important things before taking any medication is to learn about its potential side effects, and taking prednisolone is no exception. Prednisolone is a steroid mainly used to prevent inflammation in the body; arthritis and lupus are just two of the conditions for which doctors prescribe it. Side effects of taking the drug range from mildly serious to severe, can affect several areas of the body and include nausea, acne, insomnia, eye problems, skin issues and severe depression among several others.

Prednisolone may have an affect on the skin, including impairing the ability for a wound to heal, causing the skin to thin and being a cause of acne and increased sweating. Itchy skin may also happen as a result of dry skin or hives and could be a sign of an allergic reaction. Although some of these are considered less serious side effects of prednisolone, it's still beneficial to contact a dermatologist or general doctor who can recommend a course of action to relieve the discomfort.

Some of the more serious side effects of prednisolone have to do with the eyes, so it is important to contact a doctor immediately if any issues occur. There may be blurred vision and eye pain, such as burning or pressure. As a result, glaucoma or other eye problems could develop, especially if the symptoms are left unchecked by a doctor.

Other side effects that may occur can involve the nervous system. Headaches and dizziness are two common side effects. Convulsions, seizures and intense headaches and dizziness are severe side effects of prednisolone that require immediate attention by a doctor.

Any side effects of prednisolone that involve the muscles or bones require urgent medical care. Some of the side effects include muscle weakness and pain in the muscles or bones. Osteoporosis and fractures may occur, especially if initial symptoms persist and aren't checked.

Additional side effects of prednisolone include problems with the menstrual cycle, increase in weight, severely high blood pressure, tarry or bloody stools, depression, swelling and infection. There may also be breathing problems, specifically experiencing shortness of breath. These are not considered common side effects of the medication and immediate medical care is necessary.

To keep track of your body's reaction to prednisolone, consider keeping a daily journal of any side effects that occur no matter how minor they may seem. Contact a doctor if any common symptoms persist or at once if any severe side effects occur. Carefully read the instructions in the prescription description pamphlet and follow the directions of the doctor.

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