What are the Common Irbesartan Side Effects?

Irbesartan is a drug that is commonly used to treat high blood pressure, and most patients experience no irbesartan side effects at all. The most common irbesartan side effects, when they are present, include relatively mild conditions such as heartburn, diarrhea, dizziness, tiredness and sore throat. More serious side effects such as fainting, swelling, hives, impaired sexual ability, yellowing of the skin or eyes and pain during urination are possible but uncommon, and they require prompt medical attention.

This drug is available with a prescription to treat high blood pressure, either by itself or with other blood pressure medications. Irbesartan reduces blood pressure by relaxing the blood vessels, causing them to expand. Doctors might also prescribe irbesartan to patients who have diabetes to protect the kidneys from damage.

Most patients are able to take the drug without experiencing any irbesartan side effects. Diarrhea is the most common side effect, affecting about one out of every 30 patients. Heartburn and stomach discomfort are also relatively common, affecting one in 50 patients. Other mild irbesartan side effects include lightheadedness, blurred vision, tiredness, mild anxiety, runny nose and pain in the joints. If any of these problems persists or becomes worse, consultation with a doctor is recommended.

Serious irbesartan side effects are much less common and can be dangerous. Patients should advise the prescribing doctor of any allergies, especially noting known allergies to angiotensin-converting enzyme (ACE) inhibitors. Severe allergic reactions can become life threatening if the throat swells and closes off the airway. If the patient experiences symptoms such as hives, swelling or difficulty breathing, immediate medical care is essential.

Other serious irbesartan side effects include changes to the amount and color of the patient’s urine, fainting, decreased sexual ability or a yellow tinge to the skin or eyes. Each of these conditions is exceptionally rare, but when present, it represents a serious threat to the patient’s well-being. The doctor should be notified immediately of any of these conditions. Patients can prevent these irbesartan side effects by informing the prescribing doctor of any serious ongoing or previous medical conditions, especially liver or kidney disease or dysfunction, severe dehydration or high potassium levels in the blood.

Pregnant and breastfeeding women should not take irbesartan. Irbesartan can be very dangerous — even fatal — to unborn children. Women should use a reliable form of birth control while taking the drug. Before attempting to become pregnant, any woman who is taking irbesartan should consult with her doctor.