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How Effective Is Paroxetine for Depression?

By Madeleine A.
Updated: May 17, 2024

Using paroxetine for depression has been shown to reduce symptoms of depression, obsessive-compulsive disorder, and anxiety. Depression can occur as the result of a traumatic event, certain medical conditions and medications. In addition, depressive and anxiety disorders may also be related to genetics and family history. Although taking paroxetine for depression may help improve mood, doing so may cause significant side effects.

People who take paroxetine for depression may experience side effects such as nausea, vomiting, diarrhea, and loss of appetite. Paroxetine can, however, increase appetite and cause a significant weight gain. It can also contribute to a condition known as serotonin syndrome. This can occur in response to fluctuations in serotonin levels and can cause shaking, confusion, diarrhea, and lack of coordination. This condition is serious and those experiencing it should get immediate medical attention.

Although taking paroxetine for depression also can help with symptoms of anxiety, it is important to note that the drug can also cause an increase in anxiety. Symptoms such as heart palpitations, shortness of breath, and tremors may occur. When the dosage is reduced or when the drug is discontinued altogether, symptoms typically resolve. Antidepressants should never be discontinued without first consulting with the physician. Doing so can prove detrimental, both physically and psychologically.

Since weight gain is one of the most common side effects of those taking paroxetine for depression, the physician may recommend a weight management program. In addition to incorporating a healthy eating plan into a paroxetine regimen, the physician may also suggest an exercise program to help control weight. Incorporating healthy eating and exercise programs may help elevate the mood in patients suffering from depression.

Other side effects of paroxetine include insomnia, fatigue, and sleepiness. Just like with other side effects, adjusting the dosage of paroxetine may help alleviate these symptoms. If, however, side effects become severe or prevent the patient from doing his normal activities, the doctor may recommend an alternative treatment plan. Alternatives to paroxetine include other antidepressant medications, cognitive behavioral therapy (CBT), dietary changes, and physical activity.

Depression is a common condition and can cause feelings of sadness or hopelessness, changes in sleeping and eating habits, and sometimes even physical pain. In addition, depression occurs in people of all ages, including children. Also, depression can either be temporary or chronic, but is generally very treatable. Using paroxetine for depression is only one treatment option, and if it proves to be ineffective, the physician can suggest other methods of treatment.

WiseGeek is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
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