We are independent & ad-supported. We may earn a commission for purchases made through our links.

Advertiser Disclosure

Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.

How We Make Money

We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently from our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

How Effective Is Infliximab for Ulcerative Colitis?

By B. Chisholm
Updated May 17, 2024
Our promise to you
WiseGeek is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At WiseGeek, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

Infliximab for ulcerative colitis is used effectively in patients with moderate to severe disease who do not respond adequately to first line treatment. It is given by slow intravenous injection under medical supervision and is available usually by prescription only. Infliximab is known by different trade names in different countries according to manufacturer.

Ulcerative colitis is an inflammatory disease of the bowel which usually affects the tissue of the colon and rectum. It is a chronic disease which may go through latent, or remission, periods, but has no cure. Treatment is symptomatic. The symptoms, depending on the severity and which part of the colon is affected, may include pain, cramping and bloody diarrhea. If left untreated, some forms of severe ulcerative colitis may result in serious complications.

While the exact cause of ulcerative colitis is not known, it seems likely that genetics and/or an autoimmune reaction may trigger it. It usually develops slowly, over time, and results in inflammation and ulceration of the bowel and the resultant debilitating symptoms. Once diagnosed, the treating doctor will decide on the best treatment on a case-by-case basis.

Drugs used to treat ulcerative colitis may include anti-diarrheals, pain medications and anti-inflammatories such as sulfasalazine and corticosteroids. If the patient’s symptoms do not respond sufficiently, immunosuppressant drugs such as azathioprine or infliximab may be given. In some cases an antibiotic may be necessary. The proposed mechanism by which infliximab works for ulcerative colitis is by reducing inflammatory cell movement and encouraging healing of the ulcers.

After deciding to use infliximab for ulcerative colitis, the doctor will explain the possible side effects which may be experienced. These include allergic reactions, dizziness and headache. The patient may be more susceptible to infections during treatment with infliximab for ulcerative colitis.

As with any medication, interactions may occur. The prescribing doctor should be informed of any other drugs, including homeopathic, over-the-counter and complementary medications. Pregnancy, desired pregnancy and lactation should also be discussed.

When using infliximab for ulcerative colitis it is usually given as a single dose, then two weeks later, four weeks after that and then eight week intervals. It is usually administered in the hospital or the doctor's clinics as it is given by slow infusion over a couple of hours. Due to the risk of adverse effects when using infliximab for ulcerative colitis, the patient may be given some medication prior to administration to minimize the chance of side effects. Should adverse effects occur at any time during treatment, medical advice should be sought.

WiseGeek is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.

Discussion Comments

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.