I have a Bengal cat with this enzyme deficiency. I just found out about it last week. Our veterinarian said that he recently read a report about pyruvate kinase deficiency becoming widespread among Bengal cats because of breeding. He recommended that we get our cat tested. We did and he has it.
Unfortunately, there is little we can do other than just take really good care of him. The vet said that he looks healthy and happy for now. We don't know how long he will be able to live, as it's sure to shorten his life-span. We also can't have him operated on for anything since he wouldn't be able to make it.