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What is Hormone Replacement Therapy?

Mary McMahon
Mary McMahon
Mary McMahon
Mary McMahon

Hormone replacement therapy (HRT), also known as hormone replacement treatment, is a drug regimen which is designed to supplement hormones naturally created by the body. When the body ceases to produce these hormones, typically due to menopause, hormone replacement therapy can keep hormone levels stable, thus reducing the health effects of a decline in hormone production.

This medical treatment is used most commonly to treat menopausal women, or women who have experienced hysterectomies. Without the use of hormone replacement therapy, these women would experience a number of symptoms as the production of sex hormones declined, including hot flashes, mood swings, and vaginal dryness. Many women find these symptoms uncomfortable or debilitating, so they choose to pursue hormone replacement therapy.

There is disagreement in the medical community as to the safety and efficacy of hormone replacement therapy (HRT) during menopause.
There is disagreement in the medical community as to the safety and efficacy of hormone replacement therapy (HRT) during menopause.

Menopause is usually diagnosed when a woman has failed to experience a menstrual cycle for at least one year. Many doctors believe that administering hormone replacement therapy as early in menopause as possible is much more beneficial, and safer for the woman. The use of hormone replacement therapy, in addition to reducing the uncomfortable symptoms of menopause, will also reduce the risk of heart disease and osteoporosis, two conditions for which older women tend to be at greater risk. However, hormone replacement therapy is not entirely without risk. Studies have shown that it can increase blood clots, risks of certain cancers, and stroke.

Progesterone supplements are available in the form of vaginal suppositories.
Progesterone supplements are available in the form of vaginal suppositories.

There are many types of hormone replacement therapy, with most including some form of estrogen, and some form of progesterone. The drugs can be administered through pills, injections, creams, skin patches, and suppositories, and the dosages may vary widely. Generally, using a low dosage and keeping a close eye on the health of the patient is recommended, with the precise dosage being determined by the severity of the symptoms of menopause. There are also some cases in which hormone replacement therapy is not advised, making it important to discuss one's medical history with a doctor before embarking on hormone treatment.

Hormone replacement therapy may be recommended for cases of severe menopausal discomfort.
Hormone replacement therapy may be recommended for cases of severe menopausal discomfort.

In addition to being used to treat women going through menopause, HRT is also used by transgendered people. Typically hormones are administered after a lengthy period in therapy which allows the patient to fully explore his or her gender issues, and the hormones are given by injection. The use of sex hormones essentially allows the patient to go through puberty again, developing the secondary sexual characteristics of the gender which he or she feels most closely aligned with.

Mary McMahon
Mary McMahon

Ever since she began contributing to the site several years ago, Mary has embraced the exciting challenge of being a WiseGEEK researcher and writer. Mary has a liberal arts degree from Goddard College and spends her free time reading, cooking, and exploring the great outdoors.

Learn more...
Mary McMahon
Mary McMahon

Ever since she began contributing to the site several years ago, Mary has embraced the exciting challenge of being a WiseGEEK researcher and writer. Mary has a liberal arts degree from Goddard College and spends her free time reading, cooking, and exploring the great outdoors.

Learn more...

Discussion Comments

mendocino

It appears that alcohol and hormones do not mix at all. In any hormone therapy, intake of alcohol increases the risk of breast cancer. Even one or two drinks increased the risk by three times in a Danish study.

The belief is that alcohol prevents estrogen from metabolizing, leaving it in the bloodstream, and excess amount of estrogen in the bloodstream is linked with breast cancer.

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    • There is disagreement in the medical community as to the safety and efficacy of hormone replacement therapy (HRT) during menopause.
      By: Peter Atkins
      There is disagreement in the medical community as to the safety and efficacy of hormone replacement therapy (HRT) during menopause.
    • Progesterone supplements are available in the form of vaginal suppositories.
      By: Magalice
      Progesterone supplements are available in the form of vaginal suppositories.
    • Hormone replacement therapy may be recommended for cases of severe menopausal discomfort.
      By: forestpath
      Hormone replacement therapy may be recommended for cases of severe menopausal discomfort.