What is Dyrenium®?

Dyrenium® is a brand name for the generic medication triamterene. It is prescribed to treat edema, which is a condition in which the patient's tissues hold excess amounts of fluid. Fluid retention may be caused by several medical conditions, including congestive heart failure, liver cirrhosis, or kidney problems. Dyrenium® is classified as a potassium-sparing diuretic, or a “water pill.” That means that it works by stimulating the kidneys to eliminate excess water and salt, however unlike some diuretics, it will not eliminate potassium.

This medication, which is available in the form of a capsule, is taken by mouth once or twice daily. Patients will typically be advised to take the capsule after breakfast and lunch, if they take two pills, or only after breakfast. Taking the medication in the evening is not advised, as it can increase nighttime urination.

Dyrenium® may cause some side effects, including headache, dizziness, and vomiting, which should be reported to the doctor if they become troublesome. Patients should go to the hospital if they experience more serious side effects, such as irregular or slow heartbeat, problems breathing, and pain in the upper right area of the stomach. Flu-like symptoms, muscle weakness, and excessive fatigue may occur. Loss of appetite and unusual bruising or bleeding have also been reported.

In addition to taking Dyrenium®, patients should follow the doctor's healthy lifestyle guidelines for a successful treatment. They will be advised to consume a diet that is low in sodium. It is essential to avoid taking potassium tablets, as Dyrenium® allows the body to retain potassium. Some salt substitutes also contain potassium. The doctor may also advise against consuming too many foods rich in potassium, such as bananas, orange juice, and raisins.

This medication is not intended for use in children, as safety has not been determined, as of 2011. Elderly patients should use Dyrenium® with caution, as they may be more susceptible to side effects. The medicine may make the skin more prone to sunburn, so patients should use sunscreen and avoid excessive exposure to sunlight. Women who are pregnant or breastfeeding should use this drug with caution after discussing risks with their physicians. It is unknown whether it causes birth defects or if it passes into breast milk, as of 2011.

Before taking Dyrenium®, patients must disclose all other medications and supplements they take. Nonsteroidal anti-inflammatory drugs (NSAIDs), diabetes medications, and other diuretics may interact with it. In addition, the use of Dyrenium® is contraindicated in patients with liver disease, kidney disease, and kidney stones.