What Is Diphenhydramine Syrup?

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  • Written By: Meshell Powell
  • Edited By: Melissa Wiley
  • Last Modified Date: 01 February 2020
  • Copyright Protected:
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Diphenhydramine syrup is a type of medication known as an antihistamine and is available both with and without a prescription. It can be used to treat a variety of medical conditions, including cough, allergic reactions, and Parkinson's disease. Vertigo and motion sickness may also be treated with this medication. Those with diabetes can request a prescription for sugar-free diphenhydramine syrup. Side effects of diphenhydramine syrup may include dizziness, irregular heartbeat, or muscle twitches.

An antihistamine is used primarily to treat allergies, although antihistamines have proved useful in treating other medical conditions as well. Diphenhydramine syrup is used primarily for children and those who have trouble swallowing pills. In most cases, the over-the-counter formulations are sufficient in treating allergic conditions, although stronger prescription formulations are also available.

Allergic symptoms that may be successfully treated by diphenhydramine syrup include itching and the development of a rash that may or may not include hives. Seasonal allergies that cause coughing, itchy and watery eyes, and a runny or stuffy nose may also be treated with this medication. Severe allergic symptoms that include swelling of the face, tongue, or throat should be treated as a medical emergency, especially if the patient also experiences difficulty breathing.


Additional medical conditions that may be treated with diphenhydramine syrup include vertigo, motion sickness, and Parkinson's disease. Motion sickness and vertigo tend to cause nausea, and antihistamines have been found to block the portion of the brain that causes nausea in these conditions. This medications may help to control some of the tremors and stiffness associated with Parkinson's disease.

Some of the most commonly reported side effects of using diphenhydramine syrup include dizziness and drowsiness. Extra caution should be taken when performing tasks that require intense focus or concentration when using this medication. Some patients may also experience muscle twitches or an irregular heartbeat. Although these symptoms are usually mild, a doctor should be consulted if they become persistent or severe.

A doctor should be consulted before using diphenhydramine syrup, even in the over-the-counter form, as this drug may not be recommended for all patients. Those who smoke or use an excessive amount of caffeine should discuss the use of this medication with a medical professional. Other medications, especially those that are also used to treat allergies, may not interact well with this drug. Diabetic patients should ask the doctor for a sugar-free formulation so that blood sugar levels are not affected.



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