What is Cefotetan?

Cefotetan is an injectable antibiotic a doctor may prescribe for treatment or prevention of bacterial infection. This medication, known by the brand name Cefotan®, is part of the second generation class of cephalosporins and the manufacturer makes it semisynthetically. Doctors may administer the drug in a hospital or provide directions on how to use it at home if a patient requires a series of injections, but does not need to remain in the hospital for treatment.

This medication works by killing bacteria. It can be injected into a number of sites, with the buttocks being a common choice. It is important to rotate injection sites and to take the medication around the same time every day. The medication can interact negatively with other antibiotics and some other medications. Patients should be careful to discuss contraindications before they start cefotetan therapy, in case they are at risk because of a drug they are already taking or a past history of allergies. In addition, it is important to avoid drinking alcohol while on this medication and for several days afterward.

Doctors may recommend cefotetan for treatment of a variety of surface infections in areas like the skin, sinuses, and ears. It is also used for urinary tract and gynecological infections, and is active against a range of bacteria. The broad spectrum nature of cefotetan can make it appealing for prophylaxis, where the goal is to prevent infection by loading a patient's body with antibiotics so bacteria cannot colonize and thrive. Patients undergoing surgery or at risk of infections for other reasons may be put on prophylaxis for safety.

Common cefotetan side effects include nausea, vomiting, headaches, and mild skin rashes. Patients who experience shortness of breath, severe diarrhea, large rashes, and other significant discomfort should address these side effects with a physician. It is possible the patient may have an allergic response to the medication, or that the bacteria are resisting treatment and another medication will be necessary to successfully manage the infection.

Patients taking cefotetan at home will be provided with detailed instructions and a demonstration so they can administer the medication safely. Needles should be properly disposed of to reduce the risk of injuries or transmission of infection, and any unused cefotetan solution should also be securely discarded. If a patient is worried about administering injections, it may be possible to arrange home visits from a nurse or doctor to administer the drug, or the patient can ask a family member or friend for help.