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What is Cefazolin Sodium?

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  • Written By: Sonal Panse
  • Edited By: Bronwyn Harris
  • Last Modified Date: 13 November 2019
  • Copyright Protected:
    2003-2019
    Conjecture Corporation
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Cefazolin sodium, which is available under the brand names Ancef® and Zolicef®, is an antibiotic drug that is prescribed to patients suffering from bacterial infection. It is highly recommended as an urinary tract medication, and has been found to be very effective against stomach, lung, blood and skin infections caused by bacteria. The drug is administered intravenously or by injection.

When cefazolin sodium encounters bacteria, the drug penetrates the organism's cellular wall membrane and prevents the penicillin binding proteins that are present here from forming strong peptidoglycan link chains. The formation of these cross link chains is what strengthens the bacterial cell wall, and when they are not formed or are poorly formed, the cell wall is weakened. The bacteria is then not able to proliferate, and the bacterial infection should wane.

As with most medications, cefazolin sodium should only be taken under prescription from a qualified medical practitioner. It is essential to ascertain beforehand that the patient does not have any kind of allergic reactions to cefazolin sodium or any other cephalosporin medications. If the patient happens to be on any other prescription drugs, it is also necessary to check that taking these simultaneously will not lead to any negative reactions with cefazolin sodium. The drug may not be recommended for people with medical histories of kidney, liver and gastrointestinal problems, people with diabetes, and women who are pregnant or breastfeeding.

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If prescribed, cephazolin sodium should be stored and used exactly as directed. A cool, dry place that cannot be easily accessed by children and pets is recommended for storage. The cephazolin sodium solution should be checked every time prior to use to make sure that it is clear and there are no signs of any contamination. The solution should not be used if there happen to be any particles floating about in it, or if the fluid looks clouded or discolored. It is important to take the drug only in the prescribed amount and on the prescribed schedule; if patients want to make dosage or schedule changes, or stop the drug therapy altogether, they should do so only after consulting their health provider.

Some patients make experience mild to severe side effects after taking cefazolin sodium. The side effects can include stomachaches, diarrhea, vomiting, skin rashes, skin bruising, breathing difficulties and sore throat. It will be necessary to get in touch with the doctor if these symptoms are severe.

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