What Is Amikacin Sulphate?

Amikacin sulphate refers to the sulphate salt form of the antibiotic drug amikacin. This medication is considered to be a broad spectrum antibiotic, because it is effective at treating a variety of bacterial infections. Often, it is used to treat infections that have resisted other types of drugs. When taken either as an injection or in an oral form, it can treat bacterial health conditions in the respiratory system, urinary tract, skin, nervous system, and many other types of tissue. Its efficacy can allow for many types of germs to be killed, but it also carries certain risks that can sometimes restrict its use.

Many people take an amikacin sulphate dosage that remains fairly constant, regardless of the type of infection that is being treated. Usually, a dose of 250 milligrams (mg) to 400 mg is taken every 8 hours, for as long as 7 to 10 days. Alternately, slightly larger amounts between 375 mg and 600 mg can be taken just twice a day. Children and individuals with kidney damage may take lower doses than these, however, due to the fact that these people usually do not clear this drug from their body as quickly as healthy adults. Lesser amounts of amikacin can therefore help to reduce the risk of side effects.

Amikacin sulphate, like most other drugs, carries a potential to cause side effects. These adverse effects are usually mild for most individuals, and may even disappear after a few days of treatment. Nausea, vomiting, diarrhea, and headaches usually comprise the majority of side effects that occur. Occasionally, more severe effects, such as a blockade of nerve signals, can occur, which can lead to hearing loss, difficulties with balance, and paralysis. Symptoms like these may require medical attention to ensure that they do not become permanent problems.

At times, there may be risks that can occur with the use of amikacin sulphate. Antibiotics like this drug may accumulate in the kidneys if individuals do not stay hydrated, leading to increased chances of serious side effects. Pregnant women sometimes choose to avoid taking this particular drug as well, as it could potentially cause harm to the fetus, leading to birth defects. Taking amikacin sulphate for long periods of time, or at high doses, may also increase the risk of adverse events, which can include liver damage, so many opt to only take it for shorter periods of time.