What Is a Mesalamine Suppository?

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  • Written By: Meshell Powell
  • Edited By: Melissa Wiley
  • Last Modified Date: 05 May 2020
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A mesalamine suppository is a prescription medication used to treat inflammatory conditions of the colon. This medication may be prescribed to treat symptoms of this inflammation such as rectal bleeding and diarrhea and may also help to decrease the amount of mucus present in the stool. The mesalamine suppository is designed to be inserted into the rectum, and it is important to carefully follow the directions provided by the doctor or pharmacist. Common side effects of this medication include headache, dizziness, or stomach pain, although more serious complications are possible. Any specific questions or concerns about the use of a mesalamine suppository in an individual situation should be discussed with a doctor or other medical professional.

Inflammatory intestinal conditions such as Crohn's disease or ulcerative proctitis may be treated with the use of a mesalamine suppository. Specific symptoms that may benefit from the use of this medication include diarrhea, rectal bleeding, and the presence of blood or mucus in the stool. This drug is thought to work by interfering with production of the chemicals that are responsible for causing inflammation and pain.

Most people are able to use the mesalamine suppository without experiencing any negative side effects. Those who do experience side effects usually report that they are not bothersome enough to cause discontinuation of the medication. Some of the most commonly reported problems associated with the use of this drug include mild to moderate stomach pain, dizziness, or headache. More serious side effects may include yellowing of the skin or eyes, chest pain, and difficulty breathing.

It is important to thoroughly wash the hands before and after the use of a mesalamine suppository. Depending on the individual situation, this medication may be used between one and three times per day. To insert the suppository, the patient usually lies on his or her left side with the knees slightly bent. The mesalamine suppository is then gently inserted into the rectum. A tiny amount of lubricating gel can be used if desired to make insertion more comfortable.

In order to gain the full benefits of the mesalamine suppository, it is best to not have a bowel movement for at least an hour following insertion. Some patients may find it helpful to lie still as long as possible after using this drug in order to hold the suppository in place long enough for it to work. The medication used in this suppository may cause staining of the skin, clothing, or other surfaces, so care should be taken to avoid any unnecessary contact.


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