What Factors Affect Lopressor® Dosage?

There are a number of factors which influence Lopressor&Reg; dosage. They include the indication for use, response and tolerance. Lopressor® contains metoprolol, a beta-blocker, which can be used to treat hypertension, angina and some other cardiovascular disorders and myocardial infarction. It may also be used for migraine prophylaxis. Metoprolol is available in most countries by prescription only and is known by different trade names in different countries.

Lopressor®, or metoprolol, works by blocking beta receptors in the heart which, in turn, reduces the effects of the chemical transmitters noradrenaline and adrenaline. These chemicals usually cause excitation so, by blocking the beta receptors, the heart slows down and blood is pumped at a lower pressure. This is how metoprolol has its effect on hypertension, or high blood pressure.

In angina, the work load on the heart is increased, usually due to narrowed arteries. By decreasing the workload of the heart, Lopressor® helps prevent angina attacks. Metoprolol may also be used, often as an injectable, after a myocardial infarction, or heart attack. The use of metoprolol for prevention of migraines has also been effective in some cases, although the mechanism of action in this indication is, as yet, unclear.

When determining the Lopressor® dosage, the prescribing doctor will usually start at the lower end of the Lopressor® dosage scale. This will then be increased on a weekly basis, according to response, the aim being optimal blood pressure. Adverse effects may be dose-related, so tolerance also plays a role in determining the optimal Lopressor® dosage for each patient. Some Lopressor® preparations are sustained-release and may be taken as a daily dose, while others may be taken twice daily. It is important to stick to the prescribed Lopressor® dosage to ensure optimal control of blood pressure or angina.

As with any medication, adverse effects may occur when taking Lopressor®. These may include shortness of breath, headache and dizziness, especially when standing up. Should any unwanted side effects occur, they should be discussed with the prescribing doctor. The dosage may be changed or an alternate class of anti-hypertensive may be prescribed if adverse effects are intolerable.

Interactions may occur with other medications, so these, including over-the-counter, homeopathic and complementary medications, should be disclosed to the doctor. Lopressor® may be contraindicated in patients with some clinical conditions so these should also be discussed with the doctor. Pregnancy, desired pregnancy and lactation should also be disclosed, as it may affect the choice of treatment.