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What are the Symptoms of SSRI Withdrawal?

Angela Crout-Mitchell
Angela Crout-Mitchell

Various symptoms of selective serotonin reuptake inhibitor (SSRI) withdrawal often affect the body in a number of ways both physically and neurologically, as may possible experience a number of other potential side effects that do not fit into either category. SSRI drugs are usually prescribed to patients by a medical doctor or psychiatrist for the treatment of clinical and situational depression, as well as for anxiety and illnesses such as bipolar disorder. These medications affect the production of serotonin in the brain, and allow patients with these disorders to experience less emotional and mental upset and stress caused by too little production of serotonin and other naturally occurring mood elevators. It is not unusual for doctors to decide to lower the dose or change the type of medication prescribed, often creating a condition known as SSRI withdrawal syndrome.

The effects of SSRI discontinuation syndrome can affect the body for one to seven weeks, and may manifest in a variety of ways. Many patients experience bouts of headaches and insomnia during the withdrawal phase. It is not uncommon for patients to also notice unexplained fatigue, as well as nausea and vomiting. In most cases, doctors will advise their patients to gradually decrease the amount of medication taken to avoid these symptoms as much as possible.

An SSRI.
An SSRI.

SSRI discontinuation syndrome can also affect how the brain functions and reacts to normal, everyday occurrences, though no damage is believed to be done and the symptoms are relatively short-lived. The most common SSRI withdrawal symptoms from a neurological point of view include dizziness and lightheaded feelings in addition to vertigo and difficulties walking. Not all patients experience every symptom and with caution, most people are able to continue with their normal activities. Patients are advised to seek medical attention if the symptoms progressively worsen or last longer than predicted.

SSRI drugs affect the production of serotonin in the brain.
SSRI drugs affect the production of serotonin in the brain.

Dealing with SSRI withdrawal may lead to some less common symptoms such as chills, muscle pain, and diarrhea. Other patients have reported problems with their skin and may experience unexplained burning, prickling, or tingling. Visual disturbances or hallucinations are other symptoms that may occur, though both are rare. Stopping antidepressants, especially quickly and with little to no step down period, can result in the patient experiencing shock-like sensations through various parts of their body as well. Patients who notice any uncommon SSRI withdrawal side effects when stopping their medication are advised to contact the prescribing doctor immediately and seek emergency medical attention if necessary.

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    • An SSRI.
      By: Andrew S.
      An SSRI.
    • SSRI drugs affect the production of serotonin in the brain.
      By: snyggg.de
      SSRI drugs affect the production of serotonin in the brain.