What Are the Most Common Nabumetone Side Effects?

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  • Written By: Meshell Powell
  • Edited By: Melissa Wiley
  • Last Modified Date: 09 August 2019
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Nabumetone side effects are usually mild and do not cause any serious health concerns, although severe side effects are possible. Some of the most frequently reported side effects of this anti-inflammatory medication include stomach upset, headaches, and ringing in the ears. More serious nabumetone side effects that should be reported to a doctor right away include abnormal bleeding, yellowing of the skin or eyes, and muscle weakness. Severe symptoms that require immediate emergency care include facial swelling, difficulty breathing, and loss of consciousness. Any new or bothersome symptoms that develop after beginning treatment with this medication should be reported to a doctor for further evaluation.

Gastrointestinal disturbances are among the most common nabumetone side effects and may be minimized by taking the medication with food or milk unless directed otherwise by a doctor. Mild nausea, vomiting, or diarrhea is not usually anything to worry about, although extra fluids should be consumed to avoid dehydration. Violent or persistent diarrhea or vomiting, especially if accompanied by fever or severe abdominal pain, should be reported to a doctor. Blood in the stool or vomit may indicate damage to the digestive tract and should be evaluated by a medical professional right away.


A mild to moderate headache and ringing in the ears are often experienced as nabumetone side effects, but a headache that develops suddenly or causes extreme pain should prompt a visit to the nearest emergency department to rule out complications such as stroke or aneurysm. Abnormal bleeding or bruising are symptoms that should be discussed with a doctor. Muscle weakness, confusion, or fluid retention may signify serious complications that require prompt medical attention. Jaundice is a medical condition that often indicates damage to the liver and is characterized by a yellowing of the skin or the white portion of the eyes.

Allergic reactions can take on a variety of forms and are among the most severe possible nabumetone side effects. Skin reactions may include itching or burning, a rash, and blistering or peeling. Respiratory symptoms such as wheezing, chest pain, or swelling of the tongue and throat may occur due to a potentially life-threatening type of allergic reaction known as anaphylaxis. Lowered blood pressure, disorientation, and loss of consciousness may also develop during an anaphylactic reaction. Emergency medical assistance is essential when an allergic reaction is suspected, as brain damage or death are possible consequences of a severe allergic response to this drug.



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