What Are the Most Common Etodolac Side Effects?

The most common etodolac side effects include gastrointestinal upset, headaches, dizziness, and congestion. This medication is a nonsteroidal antiinflammatory drug (NSAID) recommended for patients with conditions like arthritis to use as needed for pain. Recommended dosing can depend on the patient's specific case, and as with other pain medications, it is advisable to take the medication at the onset of symptoms, rather than attempting to wait out pain or soreness. Patients who use the drug as directed are at low risk of side effects.

Some gastrointestinal side effects patients may notice can include nausea, vomiting, and diarrhea. If these become persistent or worse over time, the patient may want to talk to a doctor about them. It may be possible to adjust the dosage or find a medication that does not cause gastrointestinal discomfort. Patients may also notice headaches and dizziness in connection with the medication, which can be a cause for concern if they are severe.

Nasal congestion is another of the potential etodolac side effects. Patients may experience stuffy or runny noses. This can in turn contribute to coughing and throat irritation. Chronic signs of nasal congestion may indicate that this medication is not suitable for a patient if an alternative is available. Repeated episodes of congestion can contribute to issues like sinus infections, which can potentially become extremely severe.

There are some rare etodolac side effects that can be very serious. Some patients develop gastrointestinal bleeds. Black or tarry stools, dark urine, or bloody vomit are signs of a problem. Stomach cramps and pain may also indicate potential issues with the gastrointestinal tract.

Kidney damage is another issue. Patients who notice changes in urine output, sudden weight gain or loss, or rashes should contact a doctor as they may be experiencing dangerous etodolac side effects. This can be a particular concern with patients who take high doses of the medication, as they may be at risk of overdose.

Medications related to etodolac are linked with an increased risk of stroke. There is a concern that some etodolac side effects may lead to stroke. Patients who notice slurred speech, weakness on one side of the body, or a persistent headache should contact a doctor. The sooner a stroke is identified, the better the chance of a positive outcome with minimal brain damage. Older patients, the population most likely to take etodolac, are also at elevated risk for stroke even without the medication, and it is advisable to watch out for the early warning signs of stroke to get treatment as early as possible.