What are the Different Glyburide Side Effects?

Article Details
  • Written By: A. Pasbjerg
  • Edited By: Heather Bailey
  • Last Modified Date: 30 March 2019
  • Copyright Protected:
    Conjecture Corporation
  • Print this Article

While glyburide is typically well tolerated by most people with diabetes taking it to control their blood sugar, there are several different glyburide side effects they may experience. Some of the most common problems patients experience are digestive issues like nausea or heartburn, which can be exacerbated by alcohol use. More dangerous side effects are fairly rare but still possible; some examples include high or low blood sugar levels, liver problems, and an allergic reaction to the drug. Other rare but potentially serious issues associated with glyburide use include flu-like symptoms such as fever, chills, and persistent sore throat, blurred vision, or bleeding and bruising easily. Some patients may also feel tired or weak, have an irregular heartbeat, or notice unusual weight gain.

There are several different glyburide side effects that can affect a patient's digestive system. Many people experience feelings of stomach fullness, and they may also have heartburn. Nausea and vomiting are also common; in rare cases, these symptoms may become more severe when the medication is taken with alcohol.

Some of the different glyburide side effects that can be potentially serious are extreme shifts in blood sugar levels. Certain patients may experience hypoglycemia, or low blood pressure, which causes problems like dizziness, shaking, and cold sweats. Other may get high blood sugar, or hyperglycemia, which can lead to increased urination, blurred vision, and fatigue.


Liver problems can also be a serious side effect of taking glyburide. This can cause jaundice of the skin and eyes, dark urine, and abdominal pain. In some rare cases, patients may develop hepatitis.

Another of the different glyburide side effects that is fairly rare but may be dangerous is an allergic reaction to the medication. Patients with an allergy to glyburide may develop an itchy rash or hives, have difficulty breathing, or have swelling around their mouth and throat. This type of reaction should be reported to a doctor immediately.

There are a variety of other different glyburide side effects that should also be considered serious and should indicate a call to the doctor is needed. Some patients may feel sick as if they have the flu, with fever and chills, excessive fatigue, and a sore throat that will not go away. They may have heart palpitations and chest pain, or bleed or bruise easily. Other issues can include sudden weight gain, blurred vision, and mental changes like confusion or mood swings.



Discuss this Article

Post your comments

Post Anonymously


forgot password?