What are Simvastatin Tablets?

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  • Written By: B. Chisholm
  • Edited By: A. Joseph
  • Last Modified Date: 16 July 2019
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Simvastatin tablets are are used to treat high cholesterol, also known as hypercholesterolemia. They work by reducing the amount of cholesterol in the body, thereby decreasing the risk of cholesterol blocking the blood vessels. This, in turn, decreases the risk of heart disease. The term "simvastatin tablets" refers to the generic or active ingredient. These tablets are manufactured by various companies throughout the world and are marketed under many different brand names.

The active ingredient in simvastatin tablets — simvastatin — is part of a group of medicines called 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors. The enzyme HMG-CoA reductase is responsible for making cholesterol in the body. Cholesterol, at the right levels, is involved in building healthy cells. At above-normal levels, however, cholesterol can significantly increase the risk of heart disease.

When a person's cholesterol levels are high, there is a buildup of fat in the blood vessels, which can deposit along the walls of the vessels, making it difficult for blood to flow. This causes less oxygen-rich blood to reach the heart and can increase the risk of heart attacks. Simvastatin tablets can reduce the risk by blocking the enzyme and inhibiting the manufacture of cholesterol. This lowers cholesterol levels and therefore decreases the risk of blockages forming in the blood vessels.


Simvastatin tablets should be used under the supervision of a qualified medical professional and are available by prescription only. The usual dose is 20 milligrams daily. The tablets should be taken in the evening, because most cholesterol is manufactured at night. As with any medication, simvastatin might cause adverse side effects, so patients should contact their doctor if they experience any adverse effects.

No medication can work on its own. Simvastatin tablets are not a cure, but will help to control cholesterol levels. They should be used in combination with dietary and lifestyle changes. Exercising more and reducing one's intake of cholesterol-rich foods, such as red meat, egg and whole milk products, also will help to reduce cholesterol levels. One can get the advice of a nutritional therapist or dietitian and a personal trainer to help guide him or her.

Other medications or foods, such as grapefruit juice, might interact with simvastatin tablets. For this reason, one should be sure to tell his or her doctor if he or she is taking any other medication, including over-the-counter, natural or homeopathic medications. One must also be sure to inform the doctor of any allergies or, for a woman, whether she is breastfeeding, pregnant or trying to become pregnant.



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